| Compounds | Topics | Title | Date |
|---|---|---|---|
| THC | cancer,blood cancer in vitro | Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. | Jul 2002 |
|
Action Pathway: CB2 Exposure of murine tumors EL-4, LSA, and P815 to delta-9-tetrahydrocannabinol (THC) in vitro led to a significant reduction in cell viability and an increase in apoptosis. | |||
| THC | cancer,blood cancer in vitro | Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria. | Aug 2006 |
| The data showed that THC down-regulated Raf-1/mitogen-activated protein kinase/ERK kinase (MEK)/ERK/RSK pathway leading to translocation of Bad to mitochondria. THC also decreased the phosphorylation of Akt. | |||